The International Spine Study Group works to consistently put forward high quality, meaningful research. The findings are shared via podium presentations, posters, and published manuscripts. Explore all publications from the ISSG here.
Smith JS, Lafage V, Shaffrey CI, et al. Outcomes of operative and nonoperative treatment for adult spinal deformity: A prospective, multicenter, propensity-matched cohort assessment with minimum 2-year follow-up. Neurosurgery 2016;78:851–61. Read more...
Sciubba DM, Scheer JK, Yurter A, et al. Patients with spinal deformity over the age of 75: a retrospective analysis of operative versus non-operative management. Eur Spine J 2016;25:2433–41. Read more...
Klineberg EO, Passias PG, Jalai CM, et al. Predicting extended length of hospital stay in an adult spinal deformity surgical population. Spine (Phila Pa 1976) 2016;41:E798–805. Read more...
Passias PG, Oh C, Jalai CM, et al. Predictive model for cervical alignment and malalignment following surgical correction of adult spinal deformity. Spine (Phila Pa 1976) 2016;41:E1096–103. Read more...
Passias PG, Soroceanu A, Yang S, et al. Predictors of revision surgical procedure excluding wound complications in adult spinal deformity and impact on patient-reported outcomes and satisfaction. J Bone Jt Surg - Am Vol 2016;98:536–43. Read more...
Smith JS, Ramchandran S, Lafage V, et al. Prospective Multicenter Assessment of Early Complication Rates Associated with Adult Cervical Deformity Surgery in 78 Patients. Neurosurgery 2016;79:378–88. Read more...
Smith JS, Klineberg E, Lafage V, et al. Prospective multicenter assessment of perioperative and minimum 2-year postoperative complication rates associated with adult spinal deformity surgery. J Neurosurg Spine 2016;25:1–14. Read more...
Diebo BG, Lafage R, Ames CP, et al. Ratio of lumbar 3-column osteotomy closure: patient-specific deformity characteristics and level of resection impact correction of truncal versus pelvic compensation. Eur Spine J 2016;25:2480–7. Read more...
Ferrero E, Vira S, Ames CP, et al. Analysis of an unexplored group of sagittal deformity patients: low pelvic tilt despite positive sagittal malalignment. Eur Spine J 2016;25:3568–76. Read more...
Scheer JK, Mundis GM, Klineberg E, et al. Recovery following adult spinal deformity surgery: the effect of complications and reoperation in 149 patients with 2-year follow-up. Eur Spine J 2016;25:2612–21. Read more...
Hamilton DK, Kanter AS, Bolinger BD, et al. Reoperation rates in minimally invasive, hybrid and open surgical treatment for adult spinal deformity with minimum 2-year follow-up. Eur Spine J 2016;25:2605–11. Read more...
Hostin R, O’Brien M, McCarthy I, et al. Retrospective study of anterior interbody fusion rates and patient outcomes of using mineralized collagen and bone marrow aspirate in multilevel adult spinal deformity surgery. Clin Spine Surg 2016;29:E384–8. Read more...
Lau D, Funao H, Clark AJ, et al. The clinical correlation of the hart-issg proximal junctional kyphosis severity scale with health-related quality-of-life outcomes and need for revision surgery. Spine (Phila Pa 1976) 2016;41:213–23. Read more...
Liu S, Diebo BG, Henry JK, et al. The benefit of nonoperative treatment for adult spinal deformity: Identifying predictors for reaching a minimal clinically important difference. Spine J 2016;16:210–8. Read more...
Bess S, Line B, Fu K-M, et al. The health impact of symptomatic adult spinal deformity: Comparison of deformity types to United States population norms and chronic diseases. Spine (Phila Pa 1976) 2016;41:224–33. Read more...
Jain A, Lafage V, Kelly MP, et al. Validity, reliability, and responsiveness of SRS-7 as an outcomes assessment instrument for operatively treated patients with adult spinal deformity. Spine (Phila Pa 1976) 2016;41:1463–8. Read more...
Ramchandran S, Smith JS, Ailon T, et al. Assessment of impact of long-cassette standing X-rays on surgical planning for cervical pathology: An international survey of spine surgeons. Neurosurgery 2016;78:717–24. Read more...
Smith JS, Klineberg E, Shaffrey CI, et al. Assessment of Surgical Treatment Strategies for Moderate to Severe Cervical Spinal Deformity Reveals Marked Variation in Approaches, Osteotomies, and Fusion Levels. World Neurosurg 2016;91:228–37 Read more...
Scheer JK, Passias PG, Sorocean AM, et al. Association between preoperative cervical sagittal deformity and inferior outcomes at 2-year follow-up in patients with adult thoracolumbar deformity: Analysis of 182 patients. J Neurosurg Spine 2016;24:108–15. Read more...
Park P, Okonkwo DO, Nguyen S, et al. Can a Minimal Clinically Important Difference Be Achieved in Elderly Patients with Adult Spinal Deformity Who Undergo Minimally Invasive Spinal Surgery? World Neurosurg 2016;86:168–72. Read more...
Bess S, Protopsaltis TS, Lafage V, et al. Clinical and radiographic evaluation of adult spinal deformity. J Spinal Disord Tech 2016;29:6–16. Read more...
Than KD, Park P, Fu K-M, et al. Clinical and radiographic parameters associated with best versus worst clinical outcomes in minimally invasive spinal deformity surgery. J Neurosurg Spine 2016;25:21–5. Read more...
Mundis GM, Turner JD, Deverin V, et al. A Critical Analysis of Sagittal Plane Deformity Correction With Minimally Invasive Adult Spinal Deformity Surgery: A 2-Year Follow-Up Study. Spine Deform 2017;5:265–71 Read more...
Goldschmidt E, Angriman F, Agarwal N, et al. A Novel Tool for Deformity Surgery Planning: Determining the Magnitude of Lordotic Correction Required to Achieve a Desired Sagittal Vertical Axis. World Neurosurg 2017;104:904-908.e1. Read more...
Smith JS, Shaffrey CI, Klineberg E, et al. Complication rates associated with 3-column osteotomy in 82 adult spinal deformity patients: Retrospective review of a prospectively collected multicenter consecutive series with 2-year follow-up. J Neurosurg Spine 2017;27:444–57. Read more...
Bakhsheshian J, Scheer JK, Gum JL, et al. Comparison of structural disease burden to healthrelated quality of life scores in 264 adult spinal deformity patients with 2-year follow-up: Novel insights into drivers of disability. Clin Spine Surg 2017;30:E124–31. Read more...
Than KD, Mummaneni PV, Bridges KJ, et al. Complication rates associated with open versus percutaneous pedicle screw instrumentation among patients undergoing minimally invasive interbody fusion for adult spinal deformity. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.8.FOCUS17479. Read more...
Poorman GW, Passias PG, Horn SR, et al. Despite worse baseline status depressed patients achieved outcomes similar to those in nondepressed patients after surgery for cervical deformity. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.8.FOCUS17486. Read more...
Scheer JK, Smith JS, Schwab F, et al. Development of a preoperative predictive model for major complications following adult spinal deformity surgery. J Neurosurg Spine 2017;26:736–43. Read more...
Buckland AJ, Puvanesarajah V, Vigdorchik J, et al. Dislocation of a primary total hip arthroplasty is more common in patients with a lumbar spinal fusion. Bone Jt J 2017;99B:585–91. Read more...
Uribe JS, Beckman J, Mummaneni PV, et al. Does MIS surgery allow for shorter constructs in the surgical treatment of adult spinal deformity? Neurosurgery 2017;80:489–97. Read more...
Jain A, Kebaish KM, Sciubba DM, et al. Early Patient-Reported Outcomes Predict 3-Year Outcomes in Operatively Treated Patients with Adult Spinal Deformity. World Neurosurg 2017;102:258–62. Read more...
Nunley PD, Mundis GM, Fessler RG, et al. Impact of case type, length of stay, institution type, and comorbidities on Medicare diagnosis-related group reimbursement for adult spinal deformity surgery. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.7.FOCUS17278. Read more...
Gum JL, Hostin R, Robinson C, et al. Impact of cost valuation on cost-effectiveness in adult spine deformity surgery. Spine J 2017;17:96–101. Read more...
Bakhsheshian J, Scheer JK, Gum JL, et al. Impact of poor mental health in adult spinal deformity patients with poor physical function: A retrospective analysis with a 2-year follow-up. J Neurosurg Spine 2017;26:116–24. Read more...
Scheer JK, Keefe M, Lafage V, et al. Importance of patient-reported individualized goals when assessing outcomes for adult spinal deformity (ASD): initial experience with a Patient Generated Index (PGI). Spine J 2017;17:1397–405. Read more...
Gomez JA, Lafage V, Scuibba DM, et al. Adult Scoliosis Deformity Surgery. Spine (Phila Pa 1976) 2017;42:992–8. Read more...
Jain A, Hassanzadeh H, Puvanesarajah V, et al. Incidence of perioperative medical complications and mortality among elderly patients undergoing surgery for spinal deformity: Analysis of 3519 patients. J Neurosurg Spine 2017;27:534–9. Read more...
Scheer JK, Bakhsheshian J, Keefe MK, et al. Initial Experience with Real-Time Continuous Physical Activity Monitoring in Patients Undergoing Spine Surgery. Clin Spine Surg 2017;30:E1434–43. Read more...
Eastlack RK, Mundis GM, Wang M, et al. Is There a Patient Profile That Characterizes a Patient With Adult Spinal Deformity as a Candidate for Minimally Invasive Surgery? Glob Spine J 2017;7:703–8. Read more...
Theologis AA, Safaee M, Scheer JK, et al. Magnitude, Location, and Factors Related to Regional and Global Sagittal Alignment Change in Long Adult Deformity Constructs. Clin Spine Surg 2017;30:E948–53. Read more...
Bumpass DB, Lenke LG, Gum JL, et al. Male sex may not be associated with worse outcomes in primary all-posterior adult spinal deformity surgery: A multicenter analysis. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.9.FOCUS17475. Read more...
Buckland AJ, Poorman G, Freitag R, et al. National Administrative Databases in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2017;42:1248–54. Read more...
Protopsaltis TS, Lafage R, Vira S, et al. Novel Angular Measures of Cervical Deformity Account for Upper Cervical Compensation and Sagittal Alignment. Clin Spine Surg 2017;30:E959–67. Read more...
Lafage R, Line BG, Gupta S, et al. Orientation of the Upper-most Instrumented Segment Influences Proximal Junctional Disease Following Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2017;42:1570–7. Read more...
Lafage R, Schwab F, Glassman S, et al. Age-Adjusted Alignment Goals Have the Potential to Reduce PJK. Spine (Phila Pa 1976) 2017;42:1275–82. Read more...
Passias PG, Poorman GW, Jalai CM, et al. Outcomes of open staged corrective surgery in the setting of adult spinal deformity. Spine J 2017;17:1091–9. Read more...
Kim HJ, Iyer S, Zebala LP, et al. Perioperative neurologic complications in adult spinal deformity surgery. Spine (Phila Pa 1976) 2017;42:420–7. Read more...
Hamilton DK, Kong C, Hiratzka J, et al. Patient Satisfaction after Adult Spinal Deformity Surgery Does Not Strongly Correlate with Health-Related Quality of Life Scores, Radiographic Parameters, or Occurrence of Complications. Spine (Phila Pa 1976) 2017;42:764–9. Read more...
Oh T, Scheer JK, Smith JS, et al. Potential of predictive computer models for preoperative patient selection to enhance overall quality-adjusted life years gained at 2-year follow-up: A simulation in 234 patients with adult spinal deformity. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.9.FOCUS17494. Read more...
De la Garza Ramos R, Goodwin CR, Elder BD, et al. Preoperative functional status as a predictor of short-term outcome in adult spinal deformity surgery. J Clin Neurosci 2017;39:118–23. Read more...
Diebo BG, Gammal I, Ha Y, et al. Role of Ethnicity in Alignment Compensation: Propensity Matched Analysis of Differential Compensatory Mechanism Recruitment Patterns for Sagittal Malalignment in 288 ASD Patients from Japan, Korea, and United States. Spine (Phila Pa 1976) 2017;42:E234–40. Read more...
Ferrero E, Liabaud B, Henry JK, et al. Sagittal alignment and complications following lumbar 3- column osteotomy: Does the level of resection matter? J Neurosurg Spine 2017;27:560–9. Read more...
Daniels AH, Koller H, Hiratzka SL, et al. Selecting caudal fusion levels: 2 year functional and stiffness outcomes with matched pairs analysis in multilevel fusion to L5 versus S1. Eur Spine J 2017;26:1645–51. Read more...
Hart RA, Hiratzka J, Kane MS, et al. Stiffness after Pan-Lumbar Arthrodesis for Adult Spinal Deformity Does Not Significantly Impact Patient Functional Status or Satisfaction Irrespective of Proximal Endpoint. Spine (Phila Pa 1976) 2017;42:1151–7. Read more...
Hamilton DK, Buza JA, Passias P, et al. The Fate of Patients with Adult Spinal Deformity Incurring Rod Fracture After Thoracolumbar Fusion. World Neurosurg 2017;106:905–11. Read more...
Miller EK, Neuman BJ, Jain A, et al. An assessment of frailty as a tool for risk stratification in adult spinal deformity surgery. Neurosurg Focus;43. Epub ahead of print 2017. DOI: 10.3171/2017.10.FOCUS17472. Read more...
Smith JS, Line B, Bess S, et al. The health impact of adult cervical deformity in patients presenting for surgical treatment: Comparison to United States population norms and chronic disease states based on the EuroQuol-5 dimensions questionnaire. Clin Neurosurg 2017;80:716–25. Read more...
Theologis AA, Mundis GM, Nguyen S, et al. Utility of multilevel lateral interbody fusion of the thoracolumbar coronal curve apex in adult deformity surgery in combination with open posterior instrumentation and L5-S1 interbody fusion: A case-matched evaluation of 32 patients. J Neurosurg Spine 2017;26:208–19. Read more...
Smith JS, Shaffrey CI, Lafage R, et al. Three-column osteotomy for correction of cervical and cervicothoracic deformities: alignment changes and early complications in a multicenter prospective series of 23 patients. Eur Spine J 2017;26:2128–37. Read more...
Lafage R, Bess S, Glassman S, et al. Virtual Modeling of Postoperative Alignment after Adult Spinal Deformity Surgery Helps Predict Associations between Compensatory Spinopelvic Alignment Changes, Overcorrection, and Proximal Junctional Kyphosis. Spine (Phila Pa 1976) 2017;42:E1119–25. Read more...
Mundis GM, Turner JD, Kabirian N, et al. Anterior Column Realignment has Similar Results to Pedicle Subtraction Osteotomy in Treating Adults with Sagittal Plane Deformity. World Neurosurg 2017;105:249–56 Read more...
Gum JL, Carreon LY, Kelly MP, et al. Cell Saver for Adult Spinal Deformity Surgery Reduces Cost. Spine Deform 2017;5:272–6. Read more...
Protopsaltis T, Bronsard N, Soroceanu A, et al. Cervical sagittal deformity develops after PJK in adult thoracolumbar deformity correction: radiographic analysis utilizing a novel global sagittal angular parameter, the CTPA. Eur Spine J 2017;26:1111–20. Read more...
Passias PG, Horn SR, Jalai CM, et al. Comparative analysis of perioperative complications between a multicenter prospective cervical deformity database and the Nationwide Inpatient Sample database. Spine J 2017;17:1633–40. Read more...
Poorman GW, Passias PG, Buckland AJ, et al. Comparative Analysis of Perioperative Outcomes Using Nationally Derived Hospital Discharge Data Relative to a Prospective Multicenter Surgical Database of Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2017;42:1165–71. Read more...
Grabel ZJ, Hart RA, Clark AP, et al. Adult Spinal Deformity Knowledge in Orthopedic Spine Surgeons: Impact of Fellowship Training, Experience, and Practice Characteristics. Spine Deform 2018;6:60–6. Read more...
Yagi M, Ames CP, Keefe M, et al. A cost-effectiveness comparisons of adult spinal deformity surgery in the United States and Japan. Eur Spine J 2018;27:678–84. Read more...
Passias PG, Horn SR, Poorman GW, et al. Clinical and radiographic presentation and treatment of patients with cervical deformity secondary to thoracolumbar proximal junctional kyphosis are distinct despite achieving similar outcomes: Analysis of 123 prospective CD cases. J Clin Neurosci 2018;56:121–6. Read more...
Kim HJ, Iyer S, Diebo BG, et al. Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients. Glob Spine J 2018;8:224–30. Read more...
Challier V, Henry JK, Liu S, et al. Complication Rates and Maintenance of Correction after 3- Column Osteotomy in the Elderly: Report of 55 Patients with 2-Year Follow-up. Clin Neurosurg 2018;83:973–80. Read more...
Poorman GW, Passias PG, Qureshi R, et al. Cost-utility analysis of cervical deformity surgeries using 1-year outcome. Spine J 2018;18:1552–7. Read more...
Goldschmidt E, Angriman F, Ferreyro B, et al. Design and Testing of 2 Novel Scores That Predict Global Sagittal Alignment Utilizing Cervical or Lumbar Plain Radiographs. Clin Neurosurg 2018;82:163–71. Read more...
Neuman BJ, Ailon T, Scheer JK, et al. Development and validation of a novel adult spinal deformity surgical invasiveness score: Analysis of 464 patients. Neurosurgery 2018;82:847–52. Read more...
Scheer JK, Osorio JA, Smith JS, et al. Development of a Preoperative Predictive Model for Reaching the Oswestry Disability Index Minimal Clinically Important Difference for Adult Spinal Deformity Patients. Spine Deform 2018;6:593–9. Read more...
Scheer JK, Oh T, Smith JS, et al. Development of a validated computer-based preoperative predictive model for pseudarthrosis with 91% accuracy in 336 adult spinal deformity patients. Neurosurg Focus;45. Epub ahead of print 2018. DOI: 10.3171/2018.8.FOCUS18246. Read more...
Passias PG, Jalai CM, Worley N, et al. Development of new-onset cervical deformity in nonoperative adult spinal deformity patients with 2-year follow-up. Int J Spine Surg 2018;12:725–34. Read more...
Diebo BG, Lafage V, Varghese JJ, et al. After 9 Years of 3-Column Osteotomies, Are We Doing Better? Performance Curve Analysis of 573 Surgeries with 2-Year Follow-up. Clin Neurosurg 2018;83:69–75. Read more...
Kang J, Hosogane N, Ames C, et al. Diversity in surgical decision strategies for adult spine deformity treatment: The effects of neurosurgery or orthopedic training background and surgical experience. Neurospine 2018;15:353–61. Read more...
Passias PG, Bortz C, Horn S, et al. Drivers of Cervical Deformity Have a Strong Influence on Achieving Optimal Radiographic and Clinical Outcomes at 1 Year After Cervical Deformity Surgery. World Neurosurg 2018;112:e61–8. Read more...
Iyer S, Klineberg EO, Zebala LP, et al. Dural Tears in Adult Deformity Surgery: Incidence, Risk Factors, and Outcomes. Glob Spine J 2018;8:25–31. Read more...
Hosogane N, Ames C, Matsumoto M, et al. Ethnic variations in radiographic parameters and SRS22 scores in adult spinal deformity. Clin Spine Surg 2018;31:216–21. Read more...
Passias PG, Horn SR, Oh C, et al. Evaluating cervical deformity corrective surgery outcomes at 1-year using current patient-derived and functional measures: are they adequate? J spine Surg (Hong Kong) 2018;4:295–303. Read more...
Miller EK, Vila-Casademunt A, Neuman BJ, et al. External validation of the adult spinal deformity (ASD) frailty index (ASD-FI). Eur Spine J 2018;27:2331–8. Read more...
Miller EK, Lenke LG, Neuman BJ, et al. External validation of the adult spinal deformity (asd) frailty index (asd-fi) in the scoli-risk-1 patient database. Spine (Phila Pa 1976) 2018;43:1426–31. Read more...
Reid DBC, Daniels AH, Ailon T, et al. Frailty and Health-Related Quality of Life Improvement Following Adult Spinal Deformity Surgery. World Neurosurg 2018;112:e548–54. Read more...
Eastlack RK, Ledesma JB, Tran S, et al. Home Versus Rehabilitation: Factors that Influence Disposition After Minimally Invasive Surgery in Adult Spinal Deformity Surgery. World Neurosurg 2018;118:e610–5. Read more...
Protopsaltis TS, Diebo BG, Lafage R, et al. Identifying thoracic compensation and predicting reciprocal thoracic kyphosis and proximal junctional kyphosis in adult spinal deformity surgery. Spine (Phila Pa 1976) 2018;43:1479–86. Read more...
Hart RA, Rastegar F, Contag A, et al. Inter-and intra-rater reliability of the hart-ISSG proximal junctional failure severity scale. Spine (Phila Pa 1976) 2018;43:E461–7. Read more...
Protopsaltis TS, Ramchandran S, Hamilton DK, et al. Analysis of Successful Versus Failed Radiographic Outcomes After Cervical Deformity Surgery. Spine (Phila Pa 1976) 2018;43:E733–81. Read more...
Kelly MP, Kim HJ, Ames CP, et al. Minimum Detectable Measurement Difference for HealthRelated Quality of Life Measures Varies With Age and Disability in Adult Spinal Deformity: Implications for Calculating Minimal Clinically Important Difference. Spine (Phila Pa 1976) 2018;43:E790–5. Read more...
Scheer JK, Hostin R, Robinson C, et al. Operative Management of Adult Spinal Deformity Results in Significant Increases in QALYs Gained Compared to Nonoperative Management. Spine (Phila Pa 1976) 2018;43:339–47. Read more...
Ailon T, Smith JS, Shaffrey CI, et al. Outcomes of Operative Treatment for Adult Cervical Deformity: A Prospective Multicenter Assessment with 1-Year Follow-up. Clin Neurosurg 2018;83:1031–9. Read more...
Passias PG, Jalai CM, Line BG, et al. Patient profiling can identify patients with adult spinal deformity (ASD) at risk for conversion from nonoperative to surgical treatment: initial steps to reduce ineffective ASD management. Spine J 2018;18:234–44. Read more...
Ailon T, Smith JS, Shaffrey CI, et al. Patients with Adult Spinal Deformity with Previous Fusions Have an Equal Chance of Reaching Substantial Clinical Benefit Thresholds in Health-Related Quality of Life Measures but Do Not Reach the Same Absolute Level of Improvement. World Neurosurg 2018;116:e354–61. Read more...
Uribe JS, Januszewski J, Wang M, et al. Patients with high pelvic tilt achieve the same clinical success as those with low pelvic tilt after minimally invasive adult deformity surgery. Clin Neurosurg 2018;83:270–6. Read more...
Daniels AH, Bess S, Line B, et al. Peak Timing for Complications After Adult Spinal Deformity Surgery. World Neurosurg 2018;115:e509–15. Read more...
Passias PG, Vasquez-Montes D, Poorman GW, et al. Predictive model for distal junctional kyphosis after cervical deformity surgery. Spine J 2018;18:2187–94. Read more...
Safaee MM, Scheer JK, Ailon T, et al. Predictive Modeling of Length of Hospital Stay Following Adult Spinal Deformity Correction: Analysis of 653 Patients with an Accuracy of 75% within 2 Days. World Neurosurg 2018;115:e422–7. Read more...
Passias PG, Jalai CM, Lafage V, et al. Primary drivers of adult cervical deformity: Prevalence, variations in presentation, and effect of surgical treatment strategies on early postoperative alignment. Clin Neurosurg 2018;83:651–9. Read more...