The International Spine Study Group works to consistently put forward high quality, meaningful research. The findings are shared via podium presentations, posters, and published manuscripts. Explore all publications from the ISSG here.

    Alshabab BS, Lafage R, Smith JS, et al. Evolution of Proximal Junctional Kyphosis and Proximal Junctional Failure Rates over 10 Years of Enrollment in a Prospective Multicenter Adult Spinal Deformity Database. Spine (Phila Pa 1976) 2022;47:922–30. Read more...

    Katsuura Y, Lafage R, Kim HJ, et al. Alignment Targets, Curve Proportion and Mechanical Loading: Preliminary Analysis of an Ideal Shape Toward Reducing Proximal Junctional Kyphosis. Glob Spine J 2022;12:1165–74. Read more...

    Alluri RK, Sheikh B, Elysee JC, et al. Shoulder Balance in Adult Spinal Deformity Patients Undergoing Selective Lumbar Fusion. Spine (Phila Pa 1976) 2022;47:E385–9. Read more...

    Kim HJ, Alluri RK, Lafage R, et al. Upper versus Lower Lumbar Lordosis Corrections in Relation to Pelvic Tilt - An Essential Element in Surgical Planning for Sagittal Plane Deformity. Spine (Phila Pa 1976) 2022;47:1145–50. Read more...

    Kim HJ, Yao Y-C, Shaffrey CI, et al. Neurological Complications and Recovery Rates of Patients With Adult Cervical Deformity Surgeries. Glob Spine J 2022;12:1091–7. Read more...

    Lafage R, Fong AM, Klineberg E, et al. Complication rate evolution across a 10-year enrollment period of a prospective multicenter database. J Neurosurg Spine 2022;36:1012–22. Read more...

    Lafage R, Passias P, Sheikh Alshabab B, et al. Patterns of Lumbar Spine Malalignment Leading to Revision Surgery for Proximal Junctional Kyphosis: A Cluster Analysis of Over- Versus Under-Correction. Glob Spine J. Epub ahead of print 2022. DOI: 10.1177/21925682211047461. Read more...

    Lafage R, Schwab F, Elysee J, et al. Surgical Planning for Adult Spinal Deformity: Anticipated Sagittal Alignment Corrections According to the Surgical Level. Glob Spine J 2022;12:1761–9. Read more...

    Lafage R, Smith JS, Alshabab BS, et al. When can we expect global sagittal alignment to reach a stable value following cervical deformity surgery? J Neurosurg Spine 2022;36:616–23. Read more...

    Lafage R, Smith JS, Elysee J, et al. Sagittal age-adjusted score (SAAS) for adult spinal deformity (ASD) more effectively predicts surgical outcomes and proximal junctional kyphosis than previous classifications. Spine Deform 2022;10:121–31. Read more...

    Lafage R, Smith JS, Fong AM, et al. Proximal and distal reciprocal changes following cervical deformity malalignment correction. J Neurosurg Spine 2022;37:599–606. Read more...

    Chan AK, Eastlack RK, Fessler RG, et al. Two- and three-year outcomes of minimally invasive and hybrid correction of adult spinal deformity. J Neurosurg Spine 2022;36:595–608. Read more...

    Lafage R, Virk S, Elysee J, et al. Radiographic Characteristics of Cervical Deformity (CD) Using a Discriminant Analysis: The Value of Extension Radiographs. Clin Spine Surg 2022;35:E504–9. Read more...

    Lafage R, Smith JS, Soroceanu A, et al. Predicting Mechanical Failure Following Cervical Deformity Surgery: A Composite Score Integrating Age-Adjusted Cervical Alignment Targets. Glob Spine J. Epub ahead of print 2022. DOI: 10.1177/21925682221086535. Read more...

    Le HV, Wick JB, Lafage R, et al. Surgical Factors and Treatment Severity for Perioperative Complications Predict Hospital Length of Stay in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2022;47:136–43. Read more...

    Le HV, Wick JB, Lafage R, et al. Association of findings on preoperative extension lateral cervical radiography with osteotomy type, approach, and postoperative cervical alignment after cervical deformity surgery. J Neurosurg Spine 2022;36:93–8. Read more...

    Line B, Bess S, Gum JL, et al. Opioid use prior to surgery is associated with worse preoperative and postoperative patient reported quality of life and decreased surgical cost effectiveness for symptomatic adult spine deformity; A matched cohort analysis. North Am Spine Soc J;9. Epub ahead of print 2022. DOI: 10.1016/j.xnsj.2021.100096. Read more...

    Louie PK, Iyer S, Khanna K, et al. Revision Strategies for Harrington Rod Instrumentation: Radiographic Outcomes and Complications. Glob Spine J 2022;12:654–62. Read more...

    McCarthy MH, Lafage R, Smith JS, et al. How Much Lumbar Lordosis does a Patient Need to Reach their Age-Adjusted Alignment Target? A Formulated Approach Predicting Successful Surgical Outcomes. Glob Spine J. Epub ahead of print 2022. DOI: 10.1177/21925682221092003. Read more...

    Mundis GM, Godzik J, Park P, et al. Prospective multicenter study of minimally invasive surgery for the treatment of adult spinal deformity. J Neurosurg Spine 2022;36:767–74. Read more...

    Mundis GM, Walker CT, Smith JS, et al. Kickstand rods and correction of coronal malalignment in patients with adult spinal deformity. Eur Spine J 2022;31:1197–205. Read more...

    Passias PG, Ahmad W, Kummer N, et al. Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention. Neurosurgery 2022;90:148–53. Read more...

    Passias PG, Ahmad W, Oh C, et al. Development of Risk Stratification Predictive Models for Cervical Deformity Surgery. Neurosurgery 2022;91:928–35. Read more...

    Passias PG, Bortz C, Pierce KE, et al. Comparing and Contrasting the Clinical Utility of Sagittal Spine Alignment Classification Frameworks: Roussouly Versus SRS-Schwab. Spine (Phila Pa 1976) 2022;47:455–62. Read more...

    Chou D, Lafage V, Chan AY, et al. Patient outcomes after circumferential minimally invasive surgery compared with those of open correction for adult spinal deformity: initial analysis of prospectively collected data. J Neurosurg Spine 2022;36:203–14. Read more...

    Passias PG, Alas H, Kummer N, et al. Cervical deformity patients with baseline hyperlordosis or hyperkyphosis differ in surgical treatment and radiographic outcomes. J Craniovertebr Junction Spine 2022;13:271–7. Read more...

    Passias PG, Brown AE, Bortz C, et al. Increasing Cost Efficiency in Adult Spinal Deformity Surgery: Identifying Predictors of Lower Total Costs. Spine (Phila Pa 1976) 2022;47:21–6. Read more...

    Passias PG, Frangella NJ, Williamson TK, et al. Changes in health-related quality of life measures associated with degree of proximal junctional kyphosis. Spine Deform. Epub ahead of print 2022. DOI: 10.1007/s43390-022-00607-4. Read more...

    Passias PG, Krol O, Moattari K, et al. Evolution of Adult Cervical Deformity Surgery Clinical and Radiographic Outcomes Based on a Multicenter Prospective Study: Are Behaviors and Outcomes Changing with Experience? Spine (Phila Pa 1976) 2022;47:1574–82. Read more...

    Passias PG, Krol O, Passfall L, et al. Three-Column Osteotomy in Adult Spinal Deformity: An Analysis of Temporal Trends in Usage and Outcomes. J Bone Jt Surg 2022;104:1895–904. Read more...

    Passias PG, Kummer N, Williamson TK, et al. Highest Achievable Outcomes for Patients Undergoing Cervical Deformity Corrective Surgery by Frailty. Neurosurgery 2022;91:693–700. Read more...

    Daniels AH, Durand WM, Steinbaum AJ, et al. Examination of Adult Spinal Deformity Patients Undergoing Surgery with Implanted Spinal Cord Stimulators and Intrathecal Pumps. Spine (Phila Pa 1976) 2022;47:227–33. Read more...

    PASSIAS PG, POORMAN GW, Vasquez-Montes D, et al. Predictive Analytics for Determining Extended Operative Time in Corrective Adult Spinal Deformity Surgery. Int J Spine Surg 2022;16:291–9. Read more...

    Passias PG, Naessig S, Kummer N, et al. Predicting development of severe clinically relevant distal junctional kyphosis following adult cervical deformity surgery, with further distinction from mild asymptomatic episodes. J Neurosurg Spine 2022;36:960–7. Read more...

    Passias PG, Kummer NA, Williamson TK, et al. The Additional Economic Burden of Frailty in Adult Cervical Deformity Patients Undergoing Surgical Intervention. Spine (Phila Pa 1976) 2022;47:1418–25. Read more...

    Passias PG, Segreto FA, Moattari KA, et al. Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status. Spine Deform 2022;10:901–11. Read more...

    Pellisé F, Serra-Burriel M, Vila-Casademunt A, et al. Quality metrics in adult spinal deformity surgery over the last decade: a combined analysis of the largest prospective multicenter data sets. J Neurosurg Spine 2022;36:226–34. Read more...

    Pellisé F, Vila-Casademunt A, Núñez-Pereira S, et al. Surgeons’ risk perception in ASD surgery: The value of objective risk assessment on decision making and patient counselling. Eur Spine J 2022;31:1174–83. Read more...

    Uribe JS, Koffie RM, Wang MY, et al. Are Minimally Invasive Spine Surgeons or Classical Open Spine Surgeons More Consistent with Their Treatment of Adult Spinal Deformity? World Neurosurg. Epub ahead of print 2022. DOI: 10.1016/j.wneu.2022.05.078. Read more...

    Wick JB, Le HV, Lafage R, et al. Assessment of Adult Spinal Deformity Complication Timing and Impact on 2-Year Outcomes Using a Comprehensive Adult Spinal Deformity Classification System. Spine (Phila Pa 1976) 2022;47:445–54. Read more...

    Durand WM, Babu JM, Hamilton DK, et al. Adult Spinal Deformity Surgery Is Associated with Increased Productivity and Decreased Absenteeism From Work and School. Spine (Phila Pa 1976) 2022;47:287–94. Read more...

    Durand WM, Disilvestro KJ, Kim HJ, et al. Low-Density Pedicle Screw Constructs Are Associated with Lower Incidence of Proximal Junctional Failure in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2022;47:463–9. Read more...

    Elias E, Bess S, Line B, et al. Outcomes of operative treatment for adult spinal deformity: a prospective multicenter assessment with mean 4-year follow-up. J Neurosurg Spine 2022;37:607–16. Read more...

    Elias E, Bess S, Line BG, et al. Operative treatment outcomes for adult cervical deformity: a prospective multicenter assessment with mean 3-year follow-up. J Neurosurg Spine 2022;37:855–64. Read more...

    Gum JL, Line B, Carreon LY, et al. Reaching the medicare allowable threshold in adult spinal deformity surgery: multicenter cost analysis comparing actual direct hospital costs versus what the government will pay. Spine Deform 2022;10:425–31. Read more...