The International Spine Study Group works to consistently put forward high quality, meaningful research. The findings are shared via podium presentations, posters, and published manuscripts. Explore all publications from the ISSG here.

    Morse KW, Lafage R, Passias P, et al. A Comparison of Three Different Positioning Techniques on Surgical Corrections and Postoperative Alignment in Cervical Spinal Deformity (CD) Surgery. Spine (Phila Pa 1976) 2021;46:567–70. Read more...

    Passias PG, Brown AE, Bortz C, et al. A Risk-Benefit Analysis of Increasing Surgical Invasiveness Relative to Frailty Status in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2021;46:1087–96. Read more...

    Neuman BJ, Harris AB, Klineberg EO, et al. Defining a Surgical Invasiveness Threshold for Increased Risk of a Major Complication Following Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2021;46:931–8. Read more...

    Lafage R, Ang B, Schwab F, et al. Depression Symptoms Are Associated with Poor Functional Status among Operative Spinal Deformity Patients. Spine (Phila Pa 1976) 2021;46:447–56. Read more...

    Klineberg EO, Wick JB, Lafage R, et al. Development and validation of a multidomain surgical complication classification system for adult spinal deformity. Spine (Phila Pa 1976) 2021;46:E267–73. Read more...

    Sciubba D, Jain A, Kebaish KM, et al. Development of a Preoperative Adult Spinal Deformity Comorbidity Score That Correlates With Common Quality and Value Metrics: Length of Stay, Major Complications, and Patient-Reported Outcomes. Glob Spine J 2021;11:146–53. Read more...

    Sheikh Alshabab B, Gupta MC, Lafage R, et al. Does Achieving Global Spinal Alignment Lead to Higher Patient Satisfaction and Lower Disability in Adult Spinal Deformity? Spine (Phila Pa 1976) 2021;46:1105–10. Read more...

    Passias P, Horn S, Lafage V, et al. Effect of age-Adjusted alignment goals and distal inclination angle on the fate of distal junctional kyphosis in cervical deformity surgery. J Craniovertebr Junction Spine 2021;12:65–71. Read more...

    Virk S, Platz U, Bess S, et al. Factors influencing upper-most instrumented vertebrae selection in adult spinal deformity patients: Qualitative case-based survey of deformity surgeons. J Spine Surg 2021;7:37–47. Read more...

    Plais N, Bao H, Lafage R, et al. Fractional Curve in Adult Spinal Deformity: Is it a Driver of or a Compensation for Coronal Malalignment? Clin Spine Surg 2021;34:E276–81. Read more...

    Horn SR, Passias PG, Passfall L, et al. Improvement in some Ames-ISSG cervical deformity classification modifier grades may correlate with clinical improvement. J Clin Neurosci 2021;89:297–304. Read more...

    Gum JL, Shasti M, Yeramaneni S, et al. Improvement in SRS-22R Self-Image Correlate Most with Patient Satisfaction after 3-Column Osteotomy. Spine (Phila Pa 1976) 2021;46:822–7. Read more...

    Passias PG, Bortz C, Pierce KE, et al. Appropriate Risk Stratification and Accounting for Age-Adjusted Reciprocal Changes in the Thoracolumbar Spine Reduces the Incidence and Magnitude of Distal Junctional Kyphosis in Cervical Deformity Surgery. Spine (Phila Pa 1976) 2021;46:1437–47. Read more...

    Daniels AH, Durand WM, Lafage R, et al. Lateral Thoracolumbar Listhesis as an Independent Predictor of Disability in Adult Scoliosis Patients: Multivariable Assessment Before and After Surgical Realignment. Neurosurgery 2021;89:1080–6. Read more...

    Yao Y-C, Kim HJ, Bannwarth M, et al. Lowest Instrumented Vertebra Selection to S1 or Ilium Versus L4 or L5 in Adult Spinal Deformity: Factors for Consideration in 349 Patients With a Mean 46-Month Follow-Up. Glob Spine J. Epub ahead of print 2021. DOI: 10.1177/21925682211009178. Read more...

    Buell TJ, Smith JS, Shaffrey CI, et al. Multicenter assessment of surgical outcomes in adult spinal deformity patients with severe global coronal malalignment: Determination of target coronal realignment threshold. J Neurosurg Spine 2021;34:399–412. Read more...

    Buell TJ, Smith JS, Shaffrey CI, et al. Operative Treatment of Severe Scoliosis in Symptomatic Adults: Multicenter Assessment of Outcomes and Complications With Minimum 2-Year Follow-up. Neurosurgery 2021;89:1012–26. Read more...

    Smith JS, Kelly MP, Yanik EL, et al. Operative versus nonoperative treatment for adult symptomatic lumbar scoliosis at 5-year follow-up: Durability of outcomes and impact of treatment-related serious adverse events. J Neurosurg Spine 2021;35:67–79. Read more...

    Passias P, Horn S, Oh C, et al. Predictive model for achieving good clinical and radiographic outcomes at one-year following surgical correction of adult cervical deformity. J Craniovertebr Junction Spine 2021;12:228–35. Read more...

    Ogura Y, Gum JL, Soroceanu A, et al. Practical answers to frequently asked questions for shared decision-making in adult spinal deformity surgery. J Neurosurg Spine 2021;34:218–27. Read more...

    Scheer JK, Lenke LG, Smith JS, et al. Outcomes of Surgical Treatment for 138 Patients with Severe Sagittal Deformity at a Minimum 2-Year Follow-up: A Case Series. Oper Neurosurg 2021;21:94–103. Read more...

    Passias PG, Alas H, Bess S, et al. Patient-related and radiographic predictors of inferior health-related quality-of-life measures in adult patients with nonoperative spinal deformity. J Neurosurg Spine 2021;34:907–13. Read more...

    Alas H, Passias PG, Brown AE, et al. Predictors of serious, preventable, and costly medical complications in a population of adult spinal deformity patients. Spine J 2021;21:1559–66. Read more...

    Virk S, Lafage R, Bess S, et al. Are the Arbeitsgemeinschaft für Osteosynthesefragen (AO) Principles for Long Bone Fractures Applicable to 3-Column Osteotomy to Reduce Rod Fracture Rates? Clin Spine Surg. Epub ahead of print 2021. DOI: 10.1097/BSD.0000000000001289. Read more...

    Pierce KE, Passias PG, Brown AE, et al. Predictors of Superior Recovery Kinetics in Adult Cervical Deformity Correction: An Analysis Using a Novel Area under the Curve Methodology. Spine (Phila Pa 1976) 2021;46:559–66. Read more...

    Pierce KE, Passias PG, Brown AE, et al. Prioritization of realignment associated with superior clinical outcomes for cervical deformity patients. Neurospine 2021;18:506–14. Read more...

    Pierce K, Passias P, Brown A, et al. Prioritization of realignment associated with superior clinical outcomes for surgical cervical deformity patients. J Craniovertebr Junction Spine 2021;12:311–7. Read more...

    Passias PG, Pierce KE, Brown AE, et al. Redefining cervical spine deformity classification through novel cutoffs: An assessment of the relationship between radiographic parameters and functional neurological outcomes. J Craniovertebr Junction Spine 2021;12:157–64. Read more...

    Chou D, Chan AY, Park P, et al. Revision Surgery Rates After Minimally Invasive Adult Spinal Deformity Surgery: Correlation with Roussouly Spine Type at 2-Year Follow-Up? World Neurosurg 2021;148:e482–7. Read more...

    Passias P, Passfall L, Horn S, et al. Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction. J Craniovertebr Junction Spine 2021;12:263–8. Read more...

    Joshi RS, Lau D, Scheer JK, et al. State-of-the-art reviews predictive modeling in adult spinal deformity: applications of advanced analytics. Spine Deform 2021;9:1223–39. Read more...

    Protopsaltis TS, Stekas N, Smith JS, et al. Surgical outcomes in rigid versus flexible cervical deformities. J Neurosurg Spine 2021;34:716–24. Read more...

    Passias P, Brown A, Alas H, et al. The impact of postoperative neurologic complications on recovery kinetics in cervical deformity surgery. J Craniovertebr Junction Spine 2021;12:393–400. Read more...

    Kim HJ, Virk S, Elysee J, et al. Surgical strategy for the management of cervical deformity is based on type of cervical deformity. J Clin Med;10. Epub ahead of print 2021. DOI: 10.3390/jcm10214826. Read more...

    Durand WM, Lafage R, Hamilton DK, et al. Artificial intelligence clustering of adult spinal deformity sagittal plane morphology predicts surgical characteristics, alignment, and outcomes. Eur Spine J 2021;30:2157–66. Read more...

    Mummaneni PV, Hussain I, Shaffrey CI, et al. The minimally invasive interbody selection algorithm for spinal deformity. J Neurosurg Spine 2021;34:741–8. Read more...

    Passias PG, Alas H, Naessig S, et al. Timing of conversion to cervical malalignment and proximal junctional kyphosis following surgical correction of adult spinal deformity: A 3-year radiographic analysis. J Neurosurg Spine 2021;34:830–8. Read more...

    Bannwarth M, Smith JS, Bess S, et al. Use of rhBMP-2 for adult spinal deformity surgery: patterns of usage and changes over the past decade. Neurosurg Focus 2021;50:1–9. Read more...

    Passias PG, Pierce KE, Naessig S, et al. At What Point Should the Thoracolumbar Region Be Addressed in Patients Undergoing Corrective Cervical Deformity Surgery? Spine (Phila Pa 1976) 2021;46:E1113–8. Read more...

    Pierce KE, Passias PG, Daniels AH, et al. Baseline Frailty Status Influences Recovery Patterns and Outcomes following Alignment Correction of Cervical Deformity. Neurosurgery 2021;88:1121–7. Read more...

    Alas H, Passias P, Diebo B, et al. Cervical deformity patients with baseline hyperlordosis or hyperkyphosis differ in surgical treatment and radiographic outcomes. J Craniovertebr Junction Spine 2021;12:279–86. Read more...

    Kim HJ, Yao Y-C, Bannwarth M, et al. Cervicothoracic Versus Proximal Thoracic Lower Instrumented Vertebra Have Comparable Radiographic and Clinical Outcomes in Adult Cervical Deformity. Glob Spine J. Epub ahead of print 2021. DOI: 10.1177/21925682211017478. Read more...

    Yagi M, Ames CP, Hosogane N, et al. Comparable satisfaction and clinical outcomes after surgery for adolescent idiopathic scoliosis in the adult (AISA) between the US and Japan. J Orthop Sci. Epub ahead of print 2021. DOI: 10.1016/j.jos.2021.08.014. Read more...