The International Spine Study Group works to consistently put forward high quality, meaningful research. The findings are shared via podium presentations, posters, and published manuscripts. Explore all publications from the ISSG here.

    Goldschmidt E, Angriman F, Agarwal N, et al. A New Piece of the Puzzle to Understand Cervical  Sagittal Alignment: Utilizing a Novel Angle δto Describe the Relationship among T1 Vertebral  Body Slope, Cervical Lordosis, and Cervical Sagittal Alignment. Clin Neurosurg 2020;86:446–51. Read more...

    Durand WM, Daniels AH, Hamilton DK, et al. Artificial Intelligence Models Predict Operative Versus Nonoperative Management of Patients with Adult Spinal Deformity with 86% Accuracy. World Neurosurg 2020;141:e239–53. Read more...

    Pierce KE, Passias PG, Alas H, et al. Does Patient Frailty Status Influence Recovery following Spinal Fusion for Adult Spinal Deformity?: An Analysis of Patients with 3-Year Follow-up. Spine (Phila Pa 1976) 2020;45:E397–405. Read more...

    Passias PG, Bortz CA, Lafage V, et al. Durability of satisfactory functional outcomes following surgical adult spinal deformity correction: A 3-year survivorship analysis. Oper Neurosurg 2020;18:118–25. Read more...

    Yanik EL, Kelly MP, Lurie JD, et al. Effect modifiers for patient-reported outcomes in operatively and nonoperatively treated patients with adult symptomatic lumbar scoliosis: a combined analysis of randomized and observational cohorts. J Neurosurg Spine 2020;33:17–26. Read more...

    Line BG, Bess S, Lafage R, et al. Effective Prevention of Proximal Junctional Failure in Adult Spinal Deformity Surgery Requires a Combination of Surgical Implant Prophylaxis and Avoidance of Sagittal Alignment Overcorrection. Spine (Phila Pa 1976) 2020;45:258–67. Read more...

    Soroceanu A, Smith JS, Lau D, et al. Establishing the minimum clinically important difference in neck disability index and modified japanese orthopaedic association scores for adult cervical deformity. J Neurosurg Spine 2020;33:441–5. Read more...

    Park P, Than KD, Mummaneni PV, et al. Factors affecting approach selection for minimally invasive versus open surgery in the treatment of adult spinal deformity: Analysis of a prospective, nonrandomized multicenter study. J Neurosurg Spine 2020;33:601–6. Read more...

    Passias PG, Segreto FA, Horn SR, et al. Fatty infiltration of the cervical extensor musculature, cervical sagittal balance, and clinical outcomes: An analysis of operative adult cervical deformity patients. J Clin Neurosci 2020;72:134–41. Read more...

    Yang J, Lafage R, Gum JL, et al. Group-based trajectory modeling: A novel approach to classifying discriminative functional status following adult spinal deformity surgery: Study of a 3-year follow-up group. Spine (Phila Pa 1976) 2020;45:903–10. Read more...

    Wang MY, Park P, Tran S, et al. Intermediate-term clinical and radiographic outcomes with less invasive adult spinal deformity surgery: patients with a minimum follow-up of 4 years. Acta Neurochir (Wien) 2020;162:1393–400. Read more...

    Segreto FA, Passias PG, Lafage R, et al. Incidence of acute, progressive, and delayed proximal junctional kyphosis over an 8-year period in adult spinal deformity patients. Oper Neurosurg 2020;18:75–82. Read more...

    Daniels AH, Reid DBC, Durand WM, et al. Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion. World Neurosurg 2020;139:e449–54. Read more...

    Virk S, Passias P, Lafage R, et al. Intraoperative alignment goals for distinctive sagittal morphotypes of severe cervical deformity to achieve optimal improvements in health-related quality of life measures. Spine J 2020;20:1267–75. Read more...

    Decker S, Lafage R, Krettek C, et al. Is sacral extension a risk factor for early proximal junctional kyphosis in adult spinal deformity surgery? Asian Spine J;14. Epub ahead of print 2020. DOI: 10.31616/ASJ.2018.0314. Read more...

    Yagi M, Ames CP, Hosogane N, et al. Lower Satisfaction After Adult Spinal Deformity Surgery in Japan Than in the United States Despite Similar SRS-22 Pain and Function Scores: A Propensity-Score Matched Analysis. Spine (Phila Pa 1976) 2020;45:E1097–104. Read more...

    Wang MY, Uribe J, Mummaneni PV, et al. Minimally Invasive Spinal Deformity Surgery: Analysis of Patients Who Fail to Reach Minimal Clinically Important Difference. World Neurosurg 2020;137:e499–505. Read more...

    Beyer G, Khalifé M, Lafage R, et al. Pelvic Compensation in Sagittal Malalignment: How Much Retroversion Can the Pelvis Accommodate? Spine (Phila Pa 1976) 2020;45:E203–9. Read more...

    Horn SR, Passias PG, Oh C, et al. Predicting the combined occurrence of poor clinical and radiographic outcomes following cervical deformity corrective surgery. J Neurosurg Spine 2020;32:182–90. Read more...

    Passias PG, Horn SR, Oh C, et al. Predicting the Occurrence of Postoperative Distal Junctional Kyphosis in Cervical Deformity Patients. Neurosurgery 2020;86:E38–46. Read more...

    Passias PG, Segreto FA, Bortz CA, et al. Probability of severe frailty development among operative and nonoperative adult spinal deformity patients: an actuarial survivorship analysis over a 3-year period. Spine J 2020;20:1276–85. Read more...

    Smith JS, Buell TJ, Shaffrey CI, et al. Prospective multicenter assessment of complication rates associated with adult cervical deformity surgery in 133 patients with minimum 1-year follow-up. J Neurosurg Spine 2020;33:588–600. Read more...

    Kim HJ, York PJ, Elysee JC, et al. Cervical, Thoracic, and Spinopelvic Compensation After Proximal Junctional Kyphosis (PJK): Does Location of PJK Matter? Glob Spine J 2020;10:6–12. Read more...

    Bortz C, Passias PG, Pierce KE, et al. Radiographic benefit of incorporating the inflection between the cervical and thoracic curves in fusion constructs for surgical cervical deformity patients. J Craniovertebr Junction Spine 2020;11:131–8. Read more...

    Kim HJ, Wang S-J, Lafage R, et al. Recurrent Proximal Junctional Kyphosis: Incidence, Risk Factors, Revision Rates, and Outcomes at 2-Year Minimum Follow-up. Spine (Phila Pa 1976) 2020;45:E18–24. Read more...

    Lafage R, Beyer G, Schwab F, et al. Risk Factor Analysis for Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery: A New Simple Scoring System to Identify High-Risk Patients. Glob Spine J 2020;10:863–70. Read more...

    Daniels AH, Reid D, Durand W, et al. Sexual Dysfunction Secondary to Lumbar Stiffness in Adult Spinal Deformity Patients Before and After Long-Segment Spinal Fusion. World Neurosurg 2020;139:e474–9. Read more...

    Protopsaltis TS, Soroceanu A, Tishelman JC, et al. Should Sagittal Spinal Alignment Targets for Adult Spinal Deformity Correction Depend on Pelvic Incidence and Age? Spine (Phila Pa 1976) 2020;45:250–7. Read more...

    Plais N, Bao H, Lafage R, et al. The clinical impact of global coronal malalignment is underestimated in adult patients with thoracolumbar scoliosis. Spine Deform 2020;8:105–13. Read more...

    Protopsaltis TS, Ramchandran S, Tishelman JC, et al. The Importance of C2 Slope, a Singular Marker of Cervical Deformity, Correlates with Patient-reported Outcomes. Spine (Phila Pa 1976) 2020;45:184–92. Read more...

    Segreto FA, Passias PG, Brown AE, et al. The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity. Oper Neurosurg 2020;18:583–9. Read more...

    Mummaneni PV, Park P, Shaffrey CI, et al. The MISDEF2 algorithm: An updated algorithm for patient selection in minimally invasive deformity surgery. J Neurosurg Spine 2020;32:221–8. Read more...

    Kim HJ, Virk S, Elysee J, et al. The morphology of cervical deformities: A two-step cluster analysis to identify cervical deformity patterns. J Neurosurg Spine 2020;32:353–9. Read more...

    Durand WM, Daniels AH, Hamilton DK, et al. The spino-pelvic ratio: a novel global sagittal parameter associated with clinical outcomes in adult spinal deformity patients. Eur Spine J 2020;29:2354–61. Read more...

    Daniels AH, Reid DB, Durand WM, et al. Upper-thoracic versus lower-thoracic upper instrumented vertebra in adult spinal deformity patients undergoing fusion to the pelvis: Surgical decision-making and patient outcomes. J Neurosurg Spine 2020;32:600–6. Read more...

    Klineberg EO, Passias PG, Poorman GW, et al. Classifying Complications: Assessing Adult Spinal Deformity 2-Year Surgical Outcomes. Glob Spine J 2020;10:896–907. Read more...

    Ames CP, Smith JS, Gum JL, et al. Utilization of Predictive Modeling to Determine Episode of Care Costs and to Accurately Identify Catastrophic Cost Nonwarranty Outlier Patients in Adult Spinal Deformity Surgery: A Step Toward Bundled Payments and Risk Sharing. Spine (Phila Pa 1976) 2020;45:E252–65. Read more...

    Cruz DL, Ayres EW, Spiegel MA, et al. Validation of the recently developed Total Disability Index: A single measure of disability in neck and back pain patients. J Neurosurg Spine 2020;32:533–41. Read more...

    Ogura Y, Gum JL, Hostin RA, et al. Cost-effectiveness of surgical treatment of adult spinal deformity: comparison of posterior-only versus anteroposterior approach. Spine J 2020;20:1464–70. Read more...

    Jain A, Yeramaneni S, Kebaish KM, et al. Cost-Utility Analysis of rhBMP-2 Use in Adult Spinal Deformity Surgery. Spine (Phila Pa 1976) 2020;45:1009–15. Read more...

    Line B, Bess S, Lafage V, et al. Counseling Guidelines for Anticipated Postsurgical Improvements in Pain, Function, Mental Health, and Self-image for Different Types of Adult Spinal Deformity. Spine (Phila Pa 1976) 2020;45:1118–27. Read more...

    Virk S, Elysee J, Gupta M, et al. Defining an Algorithm of Treatment for Severe Cervical Deformity Using Surgeon Survey and Treatment Patterns. World Neurosurg 2020;139:e541–7. Read more...

    Passias PG, Horn SR, Soroceanu A, et al. Development of a Novel Cervical Deformity Surgical Invasiveness Index. Spine (Phila Pa 1976) 2020;45:116–23. Read more...